Could neurocysticercosis be the cause of "onchocerciasis-associated" epileptic seizures?
نویسندگان
چکیده
We conducted a nodule prevalence survey in four onchocerciasis sentinel communities in Moyo and two in Kanungu districts of Uganda. Seven (33.3%) out of 21 excised "onchocercomas" (nodules) in Moyo District and excised onchocercomas from four of six persons in Kanungu District turned out to be cysts of Taenia solium. We concluded that the prediction of nodule prevalence for noninvasive rapid epidemiologic assessment (REA) to target areas for mass chemotherapy with ivermectin in the African Program for Onchocerciasis Control (APOC) supported areas may have been influenced by other pathologies. T. solium infection may be the main cause of "onchocerciasis-associated epileptic seizures" in many onchocerciasis endemic communities that have been causally linked to onchocerciasis. Lastly, widespread neurocysticercosis may be a concern in mass treatment programs that provide praziquantel (for managing schistosomiasis) or albendazole (for managing intestinal worms or lymphatic filariasis) because these drugs may kill cerebral cysticerci, resulting in severe adverse events.
منابع مشابه
The association between seizures and deposition of collagen in the brain in porcine Taenia solium neurocysticercosis
Neurocysticercosis caused by infection with Taenia solium is a significant cause of epilepsy and seizures in humans. The aim of this study was to assess the association between seizures and the deposition of collagen in brain tissue in pigs with T. solium neurocysticercosis. In total 78 brain tissue sections from seven pigs were examined histopathologically i.e. two pigs with epileptic seizures...
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متن کاملCAUSES OF INTRACTABLE SEIZURES IN A SURVEY OF 10,000 EPILEPTIC CHILDREN
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متن کاملNeurocysticercosis: association between seizures, serology, and brain CT in rural Peru.
BACKGROUND Neurocysticercosis (NCC) is the commonest helminthic CNS infection and the main cause of adult-onset seizures in developing countries, also frequent in industrialized countries because of immigration from endemic zones. Although NCC is commonly seen in individuals with seizures in endemic areas, its role as a cause of epilepsy has been questioned on the basis of the poor methodology ...
متن کاملMaternal and fetal outcome in women with epilepsy associated with neurocysticercosis.
AIM We wanted to characterize the clinical profile and outcome of pregnancy in women with epilepsy due to neurocysticercosis (NCC) enrolled in the Indian Registry of Epilepsy and Pregnancy (IREP). METHODS We identified all women with NCC in the IREP between January 2000 and September 2005. Age- and parity-matched patients without NCC were identified from the respective centers of IREP for com...
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ورودعنوان ژورنال:
- The American journal of tropical medicine and hygiene
دوره 78 3 شماره
صفحات -
تاریخ انتشار 2008